Research

Nonlinear analysis of biomagnetic signals recorded from uterine myomas

Athanasia Kotini, Achilleas N Anastasiadis, Photios Anninos, Nikoleta Koutlaki and Panagiotis Anastasiadis

Lab of Medical Physics and Department of Obstetrics and Gynaecology, Medical School, Democritus University of Thrace, University Campus, Alexandroupolis, Greece

BioMagnetic Research and Technology 2006, 4:2doi:10.1186/1477-044X-4-2

Published:	30 March 2006

Abstract

Objective

To determine if there is any non-linearity in the biomagnetic recordings of uterine myomas and to find any differences that may be present in the mechanisms underlying their signal dynamics.

Methods

Twenty-four women were included in the study. Sixteen of them were characterised with large myomas and 8 with small ones. Uterine artery waveform measurements were evaluated by use of Pulsatility Index (PI) (normal value PI<1.45).

Results

Applying nonlinear analysis to the biomagnetic signals of the uterine myomas, we observed a clear saturation value for the group of large ones (mean = 11.35 ± 1.49) and no saturation for the small ones.

Conclusion

The comparison of the saturation values in the biomagnetic recordings of large and small myomas may be a valuable tool in the evaluation of functional changes in their dynamic behavior.