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Age, cumulative cigarette smoke consumption, and lung function data of all subjects of the study. |
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| Healthy |
SAR |
IPF |
COB |
|
|
|
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| AGE (years) |
54 +/- 7 |
48 +/- 14 |
49 +/- 15 |
60 +/- 8 |
| NS/S/XS |
9/8/0 |
10/2/3 |
5/4/3 |
1/3/14 |
| Pack-years (PY) |
49 +/- 18 |
18 +/- 13 |
15 +/- 6 |
40 +/- 25 |
| FEV1 (%pred.) |
105 +/- 15 |
93 +/- 15 (*) |
82 +/- 23 (*) |
72 +/- 28 (**) |
| FEV1/VC (%pred.) |
91 +/- 10 |
94 +/- 6 (ns) |
94 +/- 15 (ns) |
69 +/- 19 (**) |
| RAW (kPaL-1s-1) |
0.22 +/- 0.08 |
0.16 +/- 0.1 (ns) |
0.22 +/- 0.14 (ns) |
0.28 +/- 0.16 (ns) |
| RV % TLC |
32 +/- 6 |
33 +/- 6 (ns) |
37 +/- 12 (ns) |
45 +/- 10 (**) |
| TGV (%pred.) |
112 +/- 25 |
89 +/- 23 (*) |
91 +/- 33 (ns) |
119 +/- 34 (ns) |
| VC (%pred.) |
118 +/- 13 |
102 +/- 17 (**) |
86 +/- 19 (**) |
103 +/- 25 (ns) |
| MEF75 (%pred.) |
107 +/- 35 |
92 +/- 17 (ns) |
90 +/- 45 (ns) |
52 +/- 37 (**) |
| MEF50 (%pred.) |
82 +/- 27 |
75 +/- 24 (ns) |
71 +/- 40 (ns) |
32 +/- 25 (**) |
| MEF25 (%pred.) |
62 +/- 27 |
48 +/- 22 (ns) |
51 +/- 27 (ns) |
22 +/- 18 (**) |
| TL,CO (%pred.) |
107 +/- 33 |
98 +/- 14 (ns) |
82 +/- 13 (**) |
92 +/- 21 (ns) |
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Relative values of lung function parameters are given as a percentage of predicted values (% pred., [27]). Values are presented as mean +/- SD. Healthy: healthy subjects, age 40 – 65 years, SAR: patients with sarcoidosis, IPF: patients with idiopathic pulmonary fibrosis, COB: patients with chronic obstructive bronchitis. FEV1: forced expiratory volume in one second, VC: vital capacity, Raw: airway resistance, RV: residual volume, TLC: total lung capacity, TGV: thoracic gas volume, MEF25, MEF50, MEF75: maximal expiratory flow at 25, 50 and 75% of VC, respectively, TL,CO: transfer factor of the lung for carbon monoxide; ns: not significant; *: p < 0.05; **: p < 0.01. | ||||
Möller et al. BioMagnetic Research and Technology 2006 4:4 doi:10.1186/1477-044X-4-4 |
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